Resting Place

September 4th, 2008 at 8:42 pm by Mark Steel
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“everyone I know
goes away
in the end…”
— Nine Inch Nails, Hurt

Playing Out a Funk (Reprise)

July 19th, 2008 at 1:21 am by Mark Steel
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     Took a little break, and then picked it up again — no pun intended.  That guitar kills my fingers. 

     They bleed … it hurts to type.

     Been working with a new company a little lately, introducing some of my customers and doing a bit of cross-promotion.  I’ve also been working on some experimental car stuff a bit and doing a bit of research. 

     But all in all, not one single bit of it makes me miss my Wildcat any less.

Playing Out a Funk

July 19th, 2008 at 12:12 am by Mark Steel
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     Ok, it seems Pink Foyd: The Wall is becoming a recurring theme.

     I’ve been sitting here most of the night, rebuilding a couple of laptops, listening to the Wall Sountrack (which is a little different than the actual album).  A bit ago, I decided to pick up the guitar and play along with it.

     My fingers are bleeding…

     I gotta either quit playing, or play more.

     But I miss my Wildcat … so I play.

“Scarred for Life” Gets a Whole New Meaning

March 1st, 2006 at 10:36 am by Sam Kelter
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The National Institute of Mental Health issued a press release on Monday (Feb 27th) about a study led by Eric Nestler, M.D., of The University of Texas Southwestern Medical Center. “Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action” (Tsankova NM, Berton O, Renthal W, Kumar A, Neve R, Nestler EJ), shows that chronic stress and depression can cause a “molecular scar” in the brains of lab mice.

“The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can’t be easily reversed,” said Nestler. “To really cure depression, we probably need to find new treatments that can remove the silencer molecules.”

While not only showing promise for future treatments of depression, it may also give some hints about about genetic predisposition to depression and antisocial behavior.